MegatrendsMegatrends: not the usual suspects, but who actually profits.View megatrends →

Metrics as of 10/17/2026, 08:49 AM (Berlin time), refresh in progress.

Sionna Therapeutics Stock

Sionna Therapeutics, Inc.

SIONNASDAQMarkt
US$3.89
-4.7% today

Company data

Sector
Healthcare
Industry
Biotechnology
Country
United States
CEO
Michael Cloonan
Employees
59
Market cap
$176 M
IPO
07/02/2025

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial;…

Sionna Therapeutics stock: price history

16/10/25-88.1 %16/10/26

1D

-4.7%

1W

-20.6%

1M

-44.7%

6M

-91.1%

YTD

-90.5%

1Y

-88.1%

2Y

–

5Y

–

10Y

–

Next earnings date

Next earnings date

04/11/2026 (in 18 days)

Volatility around earnings

~505% stronger price swings than usual

Ask the agents about Sionna Therapeutics

Analyst assessment of Sionna Therapeutics

PRICE TARGET LOW

US$5.00

CONSENSUS

US$27.40

MEDIAN

US$7.00

PRICE TARGET HIGH

US$60.00

0

STRONG BUY

3

BUY

4

HOLD

1

SELL

0

STRONG SELL

8

TOTAL · Hold

As of: 15/09/2026

ANALYST FIRMRATINGACTIONDATE
WedbushNeutralmaintain15/09/2026
GuggenheimBuy → Neutraldowngrade11/08/2026
WedbushOutperform → Neutraldowngrade11/08/2026
BTIGBuy → Neutraldowngrade10/08/2026
GuggenheimBuymaintain07/08/2026
CitizensMarket Outperformmaintain26/05/2026
Freedom BrokerBuy → Holddowngrade20/05/2026
StifelBuymaintain18/05/2026

Sionna Therapeutics stock metrics

P/E

-1.78

P/B

0.66

EV/EBITDA

-1.29

RETURN ON EQUITY

-11.2%

NET MARGIN

0.0%

DEBT/EQUITY

0.03

DIVIDEND YIELD

0.0%

AS OF

30/06/2026

Free float & liquidity

FREE FLOAT

52.2%

FLOAT SHARES

23,559,458

AVG. DAILY VOLUME (30D)

1,318,164

Insider transactions (SEC)

ROLETRANSACTIONSHARESPRICEPLAN TYPEDATE

RA CAPITAL MANAGEMENT, L.P.

10% ownerSale33,8007.46Spontaneous21/09/2026

RA CAPITAL MANAGEMENT, L.P.

10% ownerSale3,415,0116.32Spontaneous21/09/2026

Fitzpatrick Jennifer

OfficerGrant28,132–Spontaneous18/09/2026

Fitzpatrick Jennifer

OfficerGrant28,133–Spontaneous18/09/2026

McKee Charlotte

OfficerGrant50,000–Spontaneous18/09/2026
Page 1 / 5

Attention

1 mention today in US forums, about the same as yesterdayPrice since yesterday: -4.7%

Forums (Reddit)

04/0905/09

Institutional holders

FUND / INSTITUTIONSHARESCHANGEAS OF
Fortitude Family Office, LLC0-1530/09/2026
RA CAPITAL MANAGEMENT, L.P.9,905,045+030/06/2026
TPG GP A, LLC6,494,962+030/06/2026
VIKING GLOBAL INVESTORS LP3,195,181+030/06/2026
Atlas Venture Life Science Advisors, LLC2,995,602+030/06/2026
Page 1 / 3

Comparable stocks

Frequently asked questions about Sionna Therapeutics stock

What does Sionna Therapeutics do?

Sionna Therapeutics, Inc. is a company in the Healthcare sector, Biotechnology industry, headquartered in United States.

The CEO is Michael Cloonan, the company employs around 59 people.

The IPO was on 07/02/2025; the stock trades on NASDAQ under the ticker SION.

What do analysts say about Sionna Therapeutics stock?

8 analysts rate the stock, the consensus is Hold (as of 15/09/2026).

The average price target is US$27.40, ranging from US$5.00 to US$60.00, with a median of US$7.00.

This is an external assessment, not a statement by Market Jury.

When does Sionna Therapeutics report next?

The next earnings date is 04/11/2026.

Around past earnings, price swings were roughly 505% stronger than usual.

Does Sionna Therapeutics pay a dividend?

No, Sionna Therapeutics currently does not pay a dividend.

Which stocks are comparable to Sionna Therapeutics?

Comparable stocks include Vertex Pharmaceuticals, Moderna, Regeneron Pharmaceuticals, Revolution Medicines, Incyte, Exelixis, Neurocrine Biosciences and Summit Therapeutics.

How can I get Sionna Therapeutics stock analyzed?

Clicking "Analyze stock" lets five strategies assess Sionna Therapeutics against fixed, published rules and judge it bullish, neutral or bearish. The jury states where it disagrees. A free account starts with 5 credits, a quick check costs 1 credit, a full analysis 2 credits.

Not investment advice. Past performance is not an indicator of future results.