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Metrics as of 10/16/2026, 02:20 PM (Berlin time), refresh in progress.

Silence Therapeutics Stock

Silence Therapeutics plc

SLNNASDAQMarkt
US$9.35
+4.1% today

Company data

Sector
Healthcare
Industry
Biotechnology
Country
United Kingdom
CEO
Iain Gladstone Ross
Employees
88
Market cap
$442 M
IPO
08/09/2020

Silence Therapeutics plc is a London, UK-based biotechnology company specializing in the research and development of groundbreaking ribonucleic acid (RNA) therapeutics. Its therapeutic focus areas include hematological, cardiovascular, and various rare and metabolic conditions. Central to their innovative approach is…

Silence Therapeutics stock: price history

15/10/25+46.6 %15/10/26

1D

+4.1%

1W

-1.8%

1M

-25.0%

6M

+23.0%

YTD

+53.8%

1Y

+46.6%

2Y

-48.9%

5Y

-57.1%

10Y

–

Next earnings date

Next earnings date

05/11/2026 (in 19 days)

Volatility around earnings

~28% stronger price swings than usual

Silence Therapeutics stock scores

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Deterministically calculated from financial metrics, not investment advice. Updated nightly, last on 29/09/2026.

Business model & megatrends

Business model

Robust business model that benefits noticeably from at least one megatrend.

Why this value? Details with Pro only.

1 more assignment (Enabler/Second row) Pro-only.

Silence Therapeutics plc is a UK-based biotechnology company specializing in the development of RNA therapeutics. The company leverages a proprietary mRNAi GalNAc oligonucleotide discovery platform to selectively modulate genes in the liver and treat diseases such as cardiovascular disorders and rare metabolic conditions. Current revenue is generated entirely from research collaboration agreements with partners including AstraZeneca PLC, Mallinckrodt Pharma IP Trading DAC, and Hansoh Pharmaceutical Group Company Limited. Several drug candidates including SLN360 and SLN124 are currently in Phase I clinical development.

Revenue model
Licensing
Recurring revenue
None
Pricing power
Moderate
Moat
Narrow
Moat type
Efficient scale
Capital intensity
High
Customer concentration
Unknown

Suppliers & customers in our universe

Customers
AstraZeneca PLCDescription

Ask the agents about Silence Therapeutics

Analyst assessment of Silence Therapeutics

PRICE TARGET LOW

US$49.00

CONSENSUS

US$57.00

MEDIAN

US$55.00

PRICE TARGET HIGH

US$67.00

0

STRONG BUY

4

BUY

0

HOLD

1

SELL

0

STRONG SELL

5

TOTAL · Buy

As of: 11/08/2026

ANALYST FIRMRATINGACTIONDATE
Morgan StanleyOverweightmaintain11/08/2026
HC Wainwright & Co.Buymaintain17/06/2026
HC Wainwright & Co.Buymaintain13/03/2026
HC Wainwright & Co.Buymaintain16/09/2025 (older than 12 months)
Chardan CapitalBuymaintain08/08/2025 (older than 12 months)
HC Wainwright & Co.Buymaintain13/06/2025 (older than 12 months)
Chardan CapitalBuymaintain13/06/2025 (older than 12 months)
Chardan CapitalBuymaintain09/05/2025 (older than 12 months)

Silence Therapeutics stock metrics

P/E

-2.45

P/B

3.83

EV/EBITDA

-6.13

RETURN ON EQUITY

-31.9%

NET MARGIN

0.0%

DEBT/EQUITY

0

DIVIDEND YIELD

0.0%

AS OF

30/06/2026

Free float & liquidity

FREE FLOAT

79.7%

FLOAT SHARES

37,668,546

AVG. DAILY VOLUME (30D)

1,018,473

Attention

Price since yesterday: +4.1%

Search (Google Trends)

25/0730/0704/08

Institutional holders

FUND / INSTITUTIONSHARESCHANGEAS OF
Siren, L.L.C.3,311,438+400,00030/06/2026
TCG Crossover Management, LLC3,033,560+030/06/2026
Redmile Group, LLC2,164,777+030/06/2026
Nantahala Capital Management, LLC1,346,731-800,00030/06/2026
CITADEL ADVISORS LLC1,329,625+94,81830/06/2026
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Comparable stocks

Frequently asked questions about Silence Therapeutics stock

What does Silence Therapeutics do?

Silence Therapeutics plc is a company in the Healthcare sector, Biotechnology industry, headquartered in United Kingdom.

The CEO is Iain Gladstone Ross, the company employs around 88 people.

The IPO was on 08/09/2020; the stock trades on NASDAQ under the ticker SLN.

What do analysts say about Silence Therapeutics stock?

5 analysts rate the stock, the consensus is Buy (as of 11/08/2026).

The average price target is US$57.00, ranging from US$49.00 to US$67.00, with a median of US$55.00.

This is an external assessment, not a statement by Market Jury.

When does Silence Therapeutics report next?

The next earnings date is 05/11/2026.

Around past earnings, price swings were roughly 28% stronger than usual.

Does Silence Therapeutics pay a dividend?

No, Silence Therapeutics currently does not pay a dividend.

Which stocks are comparable to Silence Therapeutics?

Comparable stocks include Vertex Pharmaceuticals, Moderna, Regeneron Pharmaceuticals, argenx, Revolution Medicines, BeOne Medicines, Incyte and Genmab A/S.

How can I get Silence Therapeutics stock analyzed?

Clicking "Analyze stock" lets five strategies assess Silence Therapeutics against fixed, published rules and judge it bullish, neutral or bearish. The jury states where it disagrees. A free account starts with 5 credits, a quick check costs 1 credit, a full analysis 2 credits.

Not investment advice. Past performance is not an indicator of future results.