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Metrics as of 10/13/2026, 06:51 PM (Berlin time), refresh in progress.

Spero Therapeutics Stock

Spero Therapeutics, Inc.

SPRONASDAQMarkt
US$1.15
-2.5% today

Company data

Sector
Healthcare
Industry
Biotechnology
Country
United States
CEO
Esther Rajavelu
Employees
25
Market cap
$67 M
IPO
02/11/2017

Spero Therapeutics, Inc. is a biopharmaceutical firm in the clinical development stage, primarily focused on discovering, advancing, and commercializing innovative treatments for multi-drug resistant (MDR) bacterial infections and rare diseases within the United States. The company's pipeline includes several key…

Spero Therapeutics stock: price history

13/10/25-49.8 %13/10/26

1D

-2.5%

1W

-3.4%

1M

+1.8%

6M

-58.6%

YTD

-50.6%

1Y

-49.8%

2Y

-8.0%

5Y

-93.3%

10Y

–

Next earnings date

Next earnings date

12/11/2026 (in 26 days)

Volatility around earnings

~21% weaker price swings than usual

Ask the agents about Spero Therapeutics

Analyst assessment of Spero Therapeutics

0

STRONG BUY

6

BUY

5

HOLD

2

SELL

0

STRONG SELL

13

TOTAL · Buy

As of: 14/09/2026

ANALYST FIRMRATINGACTIONDATE
HC Wainwright & Co.Buymaintain14/09/2026
HC Wainwright & Co.Buymaintain30/01/2025 (older than 12 months)
Evercore ISI GroupOutperform → In Linedowngrade20/12/2024 (older than 12 months)
HC Wainwright & Co.Buymaintain02/12/2024 (older than 12 months)
TD CowenBuy → Holddowngrade18/11/2024 (older than 12 months)
HC Wainwright & Co.Buymaintain04/11/2024 (older than 12 months)
HC Wainwright & Co.Buymaintain03/10/2024 (older than 12 months)
HC Wainwright & Co.Buymaintain06/08/2024 (older than 12 months)

Spero Therapeutics stock metrics

P/E

8.21

P/B

1.51

EV/EBITDA

2.32

RETURN ON EQUITY

-21.6%

NET MARGIN

0.0%

DEBT/EQUITY

0.05

DIVIDEND YIELD

0.0%

AS OF

30/06/2026

Free float & liquidity

FREE FLOAT

80.1%

FLOAT SHARES

46,382,570

AVG. DAILY VOLUME (30D)

714,793

Insider transactions (SEC)

ROLETRANSACTIONSHARESPRICEPLAN TYPEDATE

Zack Debra

OfficerGrant162,311–Pre-planned06/08/2026

Jackson Scott Thomas

DirectorGrant10,000–Spontaneous25/06/2026

THOMAS FRANK E

DirectorGrant10,000–Spontaneous25/06/2026

VINK PATRICK V.J.J.

DirectorGrant10,000–Spontaneous25/06/2026

Pottage John C Jr

DirectorGrant10,000–Spontaneous25/06/2026
Page 1 / 2

Institutional holders

FUND / INSTITUTIONSHARESCHANGEAS OF
DLK Investment Management, LLC0-31,35530/09/2026
GSK PLC9,190,606+030/06/2026
PFIZER INC2,362,348+030/06/2026
VANGUARD CAPITAL MANAGEMENT LLC2,036,226+236,34630/06/2026
RENAISSANCE TECHNOLOGIES LLC947,904-241,33130/06/2026
Page 1 / 3

Dividends

EX-DATEPAY DATEAMOUNTYIELD
16/09/201507/10/2015US$0.020.5 %
17/06/201507/07/2015US$0.020.5 %
18/03/201507/04/2015US$0.020.5 %
17/12/201406/01/2015US$0.020.5 %
17/09/201407/10/2014US$0.020.5 %
Page 1 / 5

Comparable stocks

Frequently asked questions about Spero Therapeutics stock

What does Spero Therapeutics do?

Spero Therapeutics, Inc. is a company in the Healthcare sector, Biotechnology industry, headquartered in United States.

The CEO is Esther Rajavelu, the company employs around 25 people.

The IPO was on 02/11/2017; the stock trades on NASDAQ under the ticker SPRO.

What do analysts say about Spero Therapeutics stock?

13 analysts rate the stock, the consensus is Buy (as of 14/09/2026).

This is an external assessment, not a statement by Market Jury.

When does Spero Therapeutics report next?

The next earnings date is 12/11/2026.

Around past earnings, price swings were roughly -21% stronger than usual.

Does Spero Therapeutics pay a dividend?

Yes. The last dividend was US$0.02 per share, ex-date 16/09/2015, paid on 07/10/2015.

The dividend yield is 0.0% (as of 30/06/2026).

Which stocks are comparable to Spero Therapeutics?

Comparable stocks include Vertex Pharmaceuticals, Moderna, Regeneron Pharmaceuticals, Revolution Medicines, Incyte, Exelixis, Neurocrine Biosciences and Summit Therapeutics.

How can I get Spero Therapeutics stock analyzed?

Clicking "Analyze stock" lets five strategies assess Spero Therapeutics against fixed, published rules and judge it bullish, neutral or bearish. The jury states where it disagrees. A free account starts with 5 credits, a quick check costs 1 credit, a full analysis 2 credits.

Not investment advice. Past performance is not an indicator of future results.